Synopsis:
Recent revelations in microRNA (miRNA) research have implicated these small, non-coding RNA molecules as important contributors to the regulation of gene expression in plants, animals, and viruses. Hui Wang dicusses her work with Agilent Technologies in developing a sensitive miRNA microarray and exploring current questions in miRNA research related to methods for approaching a more quantitative measurement of miRNA expression. The capabilities of the miRNA microarray platform are discussed at great length, providing important preliminary research that supports the use of the platform for accurate and sensitive miRNA profiling.
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