miRNA

Open Up to Novel miRNA Profiling

Dissect novel pathways of gene regulation. Confidently identify changes in miRNA expression. Evolve with a changing miRNA research landscape.

MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNAs (19-30 nucleotides long) that serve widespread functions in post-transcriptional gene silencing. Recently, research has demonstrated that miRNAs are crucial regulators of gene expression, affecting a wide variety of cellular functions including development, proliferation, differentiation, and apoptosis. Begin your sample analysis with accurate quantification and monitoring of miRNA fractions from either total RNA or enriched small RNA fractions, using the Small RNA Kit for the 2100 bioanalyzer. Follow sample preparation by addressing your novel research questions related to miRNA expression, using Agilent's MicroRNA Profiling System, an 8 x 15K miRNA-specific microarray. This novel microarray features:

• Low Sample Input – Agilent’s innovative probe design and direct labeling protocol require just 100ng of total RNA for reliable results.


• Broad Dynamic Range – Agilent’s miRNA profiling system spans greater than 5 logs for comprehensive miRNA expression profiling.


• Precise miRNA Discrimination – Agilent’s in situ synthesis process delivers probes capable of accurate single-nucleotide discrimination between similar size and sequence miRNAs.